Dr Sarah Elizabeth Lee

Job: Researcher

Faculty: Health and Life Sciences

School/department: Leicester School of Pharmacy

Research group(s): Pharmacology

Address: De Montfort University, The Gateway, Leicester, LE1 9BH

T: +44 (0)116 257 7954

E: s.lee@dmu.ac.uk

W: http://dmu.ac.uk/hls

 

Personal profile

Lee holds a degree in chemistry from Imperial College, London and a PhD from the University of Bangor looking at the mechanism and application of the non-classical Wittig reaction with carbohydrate-derived lactones. More recently, her research has strived to understand the role of phosphorus-containing chemicals in natural and unnatural biological processes. Specific research projects have included incorporating unnatural functionalities into nucleic acids, and the role of unnatural ATPs in elucidating cell signaling processes. Her research sits within the discipline of chemical biology, although her personal research looks at the issues presented in the systematic synthesis of the necessary chemical tools to probe the biological system.

Research group affiliations

Research interests/expertise

  • Chemical synthesis (organic)
  • Modified carbohydrates
  • Modified ATPs
  • Organo-phosphorus chemistry
  • Chemistry of Phosphates
  • HPLC
  • Ion-exchange chromatography
  • Nucleosides, Nucleotides and Nucleic Acids