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Dr Mohsen Seifi

Job: Senior Lecturer in Pharmacology

Faculty: Health and Life Sciences

School/department: Leicester School of Pharmacy

Address: De Montfort University, The Gateway, Leicester, LE1 9BH

T: 0116 250 6477

E: mohsen.seifi@dmu.ac.uk

 

Personal profile

I graduated with BSc (Hons) Pharmacology degree and PhD in Neuropharmacology from the University of Portsmouth, UK. Flowing postdoctoral training, I was appointed as a Lecturer at Southampton Solent University where I contributed to the design and delivery of their new Biomedical Science degree program. Subsequently, I joined De Montfort University as a Senior Lecturer in Pharmacology in 2020 where I contribute to undergraduate and post graduate teaching within the School of Pharmacy.

I am a committed neuroscientist and have spent many years investigating the mechanisms through which cells of the nervous system communicate with one another and identifying specific alterations in such communication which underlie development of various brain and peripheral disorders. I have published my work in several high-impact factor journals, served as a reviewer for various journals and have been invited to present my research around the world.

Research group affiliations

Leicester Institute of Pharmaceutical Innovation for Integrated Care (LIPIIC)

Research interests/expertise

The nervous system controls the activity of all organs within our body. This occurs through the release of a vast array of neurotransmitters by neurons that bind to their specific neurotransmitter receptors expressed within peripheral organs. Most often, alterations in the function of neurotransmitter/neurotransmitter receptors are the main culprit for development of many brain and peripheral disorders.

The main aim of my research is to investigate the impact of negative life experiences such as repeated emotional stress and the ageing process on the expression and function of neurotransmitter systems within specific neural networks of the brain and the peripheral nervous system.

I am particularly interested in identifying specific alterations in neurotransmitter systems that account for symptoms associated with brain disorders such as anxiety and neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease, as well as gastrointestinal disorders such as inflammatory bowel disease and irritable bowel syndrome. To achieve this, I used a combination of histology, molecular biology, electrophysiology, transgenic animals, and animal behavioural assays.

Areas of teaching

  • Pharmacology
  • Neuroscience

Qualifications

  • BSc (Hons) Pharmacology
  • PhD in Neuropharmacology

Courses taught

Pharmacy MPharm , MSc in Pharmaceutical Biotechnology, Pharmaceutical and Cosmetic Science

Honours and awards

  • Guarantors of Brain Travel award (2019)
  • The Federation of European Neuroscience (FENS) Travel Grant

Membership of external committees

Member of Parkinson’s UK grant reviewing committee as research evaluator.

Membership of professional associations and societies

  • British Neuroscience Association
  • Alzheimer’s Research UK Southcoast Network

Professional licences and certificates

Home office animal licence (modules 1-4)

Externally funded research grants information

  • Alzheimer’s Research UK Pump Prime Grant, PI, The role of Syndapin-2 as a novel Aβ clearance mechanism in Alzheimer’s disease, £5,000, 2020-2021.
  • Alzheimer’s Research UK Pilot Grant, named applicant, Characterisation of enteric nervous system function of the intestine in Alzheimer’s disease, £47,000, 2015-2017.

ORCID number

0000-0002-5795-4409

mohsen-seifi