De Montfort University PhD Scholarships
Applications to scholarships for the 2023/24 academic year have now closed.
Please contact PGRscholarships@dmu.ac.uk if you have any questions.
Midlands4Cities
The AHRC-funded Midlands4Cities Doctoral Training Partnership (M4C) brings together eight leading universities across the Midlands to support the professional and personal development of the next generation of arts and humanities doctoral researchers. M4C is a collaboration between the University of Birmingham, Birmingham City University, University of Warwick, Coventry University, University of Leicester, De Montfort University, Nottingham Trent University and The University of Nottingham.
Offering you cross-institutional supervision, training, mentoring and career support to ensure that you produce world-leading research and maximise your career potential. The Doctoral Training Partnerships awards IRO 80 PhD Arts and Humanities Research Council (AHRC) studentships applicants each year.
Through the partnership we aim to deliver excellence in all aspects of research supervision and training. We will assist you in acquiring the best supervision for your field of research, you will have access to a wide range of facilities and support networks across our campuses.
See further information on the application process.
PhD Studentship: Development of Mechanistic Crystal Dissolution Model
Project description
Tablets are pre-eminent for delivering most active pharmaceutical ingredients (APIs) to patients. Prediction of drug release from a tablet is currently based on API dissolution models, typically the Noyes-Whitney equation or its modifications, which only consider the slowest mass transfer step of diffusion of solute molecules through a stagnant boundary layer. The limitation here is that other key processes are neglected, such as solvent wetting of the crystal surfaces, breakdown of solid-state bonds, solvation, diffusion through the quiescent liquid boundary layer surrounding the particle, and convection into the bulk liquid. These models assume the spherical shape of the dissolving particles, without considering crystal morphology, and hence, the specific surface chemistry of the dissolving crystals, which is particularly important for poorly water-soluble APIs.
In this project we will develop a unique crystal dissolution modelling to predict drug release from tablet accurately. Within the project the successful PhD candidate will work with the other PDRAs and PhDs, led by Professor Mingzhong Li at De Montfort University, to develop a mechanistic crystal dissolution model.
You will be a conscientious, innovative researcher who has a strong background in engineering and/or chemistry with strong skills in programming and modelling and analysis. Experience in data analysis for complex systems is preferred. The successful candidate will have opportunity to interact with our industrial partners such as the secondment.
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Funding
DMU is offering a fully-funded 3-year PhD scholarship for this work, commencing on 1 October 2024. Applications are open to Home and international students, i.e. tuition fees at Home or International level will be waived. The studentship comes with a stipend pegged at the UKRI rate, currently at £19,237 per annum.
Lead Supervisor: Professor Mingzhong Li, Professor of Crystallisation Science & Drug Delivery, Leicester School of Pharmacy
Email: mli@dmu.ac.uk
Applicants must:
- Possess a UK Honours degree with at least an upper second class (or overseas equivalent), a Masters Degree or an academic or professional qualification plus experience in their sector or industry.
- Demonstrate competence in the use of the English language. Please see section 5b of our entry criteria information for further details on meeting our English language entry criteria.
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How to apply
This is a two-stage application process.
Stage one
Please send the following documents to PGRscholarships@dmu.ac.uk:
Deadline: Thursday 23 May 2024
Stage two
Shortlisted candidates will be contacted to undergo an interview, and successful candidates will be contacted by Thursday, 6 June 2024 with a request to submit a full application through the DMU PGR Application Portal.
Deadline for full application: Thursday 20 June 2024.
Scholarship letters will be issued by Wednesday 27 June 2024.
Alumni discounts
De Montfort University offers alumni discounts for students that have previously studied with us at undergraduate or taught masters degree level. This discount is available to Home and International Students. This discount is only available to new starters and will be automatically applied if you are eligible.
Home alumni discount is £500 per year (full-time equivalent).
International alumni discount is £2,000 per year (full-time equivalent).
Additional funding opportunities
Schlumberger Foundation Faculty for the Future Fellowship
Commonwealth Scholarships
Amelia Earhart Fellowship
Education Loans | Leicestershire | The Sir Thomas White Loan Charity
The Harry James Riddleston Charity