Professor Graham Sewell

Job: Professor of Pharmacy Practice

Faculty: Health and Life Sciences

School/department: Leicester School of Pharmacy

Address: De Montfort University, The Gateway, Leicester, LE1 9BH

T: +44 (0)116 207 8289

E: graham.sewell@dmu.ac.uk

W: http://www.dmu.ac.uk

 

Personal profile

Graham Sewell has academic and professional qualifications in pharmacy, biology and chemistry, and received his doctorate from the School of Pharmacy and Pharmacology, University of Bath. Graham has held several combined appointments as Professor of Clinical Pharmacy and as a senior hospital pharmacist before joining the University of Plymouth in October 2009 to work out of discipline as Head of the School of Health Professions and Associate Dean for Research in the Faculty of Health and Human Sciences. In May 2019, Graham returned to his Pharmacy roots and joined the School of Pharmacy at De Montfort University as Professor of Pharmacy Practice.

Graham has research interests in various scientific and professional areas including oncology pharmacy, therapeutic optimisation, clinical pharmacokinetics, drug formulation and stability, environmental hazards of cytotoxic drugs and non-medical prescribing. He has more than 140 peer-reviewed research publications, abstracts, book chapters and review articles, over 80 invited keynote/plenary presentations and has directed over 20 PhD/MPhil projects to completion. Graham is best known for his work on Dose Banding of Cancer Chemotherapy, which was adopted by NHS England in 2016.

Among his varied national and international committee work, Graham was a member of the WHO Expert Committee on Cancer Pain and Palliative Care, is a member of the EORTC Pharmacology and Molecular Mechanisms Group, was elected as President of ISOPP 2006-8, and holds editorial positions for several journals. Graham has also led several international evaluation panels to review medical universities in Europe and the Far East. In 2008, the International Society of Oncology Pharmacy presented him with the Helen McKinnon Award, its highest accolade, in recognition of his research in oncology pharmacy.

Research group affiliations

Leicester Institute of Pharmaceutical Innovation for Integrated Care (LIPIIC)

Research interests/expertise

  • Novel methods of chemotherapy dosing, standardisation and therapeutic optimisation of cancer treatments.
  • Clinical Pharmacokinetics
  • Environmental and Occupational exposure issues with cytotoxic drugs.
  • Medicines Management/Medicines Optimisation
  • Aseptic preparation and QA
  • Pharmacy Public Health
  • Drug formulation and stability of drug infusions
  • Ambulatory infusional therapy for cystic fibrosis, cancer and infectious diseases.
  • “Non-medical” prescribing
  • Risk management and medication errors

Areas of teaching

Pharmacy/Pharmaceutical Sciences/Healthcare

Qualifications

  • BPharm
  • PhD
  • MRPharmS
  • MRSC, CChem
  • MBS, CBiol

Courses taught

Undergraduate and postgraduate

Honours and awards

  • Jansenn Prize awarded by School of Pharmacy and Pharmacology, University of Bath (1980).
  • Vestric Travel Award 1989 (for research in cancer chemotherapy).
  • National QC Symposium Award 1992 for research in bioanalytical methods.
  • Norton Healthcare Award, 1995 for research in derivative spectroscopy in QC.
  • McKinnon Award. Awarded for outstanding contribution to the research and practice of oncology pharmacy by International Society of Oncology Pharmacy Practitioners. Presented in Los Angeles, June 18, 2008
  • Associate Editor (Europe and Scandinavia) Journal of Oncology Pharmacy Practice (1998- ) International Editorial Advisory Board Member for Generics and Biosimilars Initiative (GaBI) Journal, 2008-

Membership of external committees

  • Chair, Research Committee of International Society of Oncology Pharmacy Practitioners 1998 – 2004
  • Member of Science Committee, ISOPP 8 Symposium, Vancouver, Canada, 7-11May, 2002.
  • Member of Science Committee, ISOPP 9 Symposium, Turin , Italy April 14 2004
  • President, International Society of Oncology Pharmacy Practitioners. March 2004 – March 2006. (Elected to this position by International ballot)
  • Chair MARCH Programme scientific panel 1999- 2010
  • Member BAPEN Research and Science Committee, 2001-2004
  • Member of Management Committee, Joint Pharmaceutical Analysis Group of Royal Society of Chemistry/ Royal Pharmaceutical Society. 2002- 2006.
  • Member National Cancer Research Network Oncology Pharmacy and Chemotherapy
  • Standardisation Committee. Nov 2003 – April 2008
  • Editorial Board Member of European Journal of Parenteral and Pharmaceutical Sciences. 2018-

Membership of professional associations and societies

  • Member of Royal Pharmaceutical Society (2014- )
  • Member of Royal Society of Chemistry (1996 - )
  • Member Biological Society (2005 - )
  • Member of International Society of Oncology Pharmacy Practitioners (2008 - )

Professional licences and certificates

  • Registered Pharmacist with General Pharmaceutical Council
  • Chartered Chemist
  • Chartered Biologist

Projects

Current projects include:

  • Evaluating the impact of Dose-Banding in Cancer Chemotherapy
  • Effect of new technologies and closed systems on the risk of occupational exposure of healthcare staff to cytotoxic drugs

Consultancy work

Numerous assignments undertaken including patent challenges, patent protection, infusion stability and compatibility studies, clinical pharmacokinetic - pharmacodynamic evaluation, medico-legal issues.

Externally funded research grants information

Grants in last 10 years include:

  • Kidani Memorial Foundation, research project, £182,250. Awarded July 2010
  • Teva Hospitals, unrestricted research grant, £20,000. Awarded Jan 2011
  • Plymouth Public Health Research Prog. research grant £15,000. Awarded Feb 2012
  • NHS Breast Screening Programme. Audit grant £10,000. Awarded March 2013
  • Vygon (France) Ltd, unrestricted research grant, compatibility of drugs with CSTD devices. £38,000. Awarded Nov 2014
  • Accord Ltd grant for drug stability studies, £29,900. Awarded Jan 2016
  • Vygon (France) Ltd, unrestricted research grant for studies on compatibility of drugs with medical devices. £41,500. Awarded Feb 2017
  • Knowledge Transfer Partnership award with Made for Life Organics, Cornwall £143,941. Awarded Oct 2017 (Lead applicant)

Case studies

Currently two case studies in VV Tracker format:

1. Dose Banding of Cancer Chemotherapy

2. Reducing Occupational and Environmental Exposure to Cytotoxic Drugs

ORCID number

0000-0002-2628-609X

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