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Dr Graham Basten

Job: Associate Head of School

Faculty: Health and Life Sciences

School/department: School of Allied Health Sciences

Research group(s): Biomedical and Environmental Health

Address: De Montfort University, The Gateway, Leicester, LE1 9BH

T: +44 (0)116 207 8639

E: gbasten@dmu.ac.uk

W: grahambastenresearch.blogspot.com

Social Media: isothiocyanates.blogspot.com


Personal profile

Dr Graham Basten is Associate Head of the School of Allied Health Sciences at De Montfort University (UK). He is also Head of the Biomedical and Medical Science Division.

He holds a PhD from the UK Government's Institute of Food Research and has researched and lectured extensively over the past 10 years on clinical biochemistry, nutrition and folate at the Universities of Sheffield and Nottingham (UK). He is a De Montfort University Teacher Fellow and has been nominated for the Vice Chancellor's Distinguished Teaching Award. As a principal lecturer in Clinical Chemistry he has written four textbooks and published several journal articles.

Graham has completed the award winning DMU Leadership, Management and Development Programme, as well as a series from the LFHE. He is an advocate of authentic leadership, 360 feedback, action learning sets and SDI.

Publications and outputs 

Click here for a lfull listing of Graham Basten's publications and outputs.|

Research interests/expertise

  • Clinical nutrition 
  • Folate
  • Glucosinolates
  • Blood test results / pathology
  • CVD (homocysteine and vascular tone) and cancer risk (uracil misincorporation)
  • Cell culture, clinical chemistry, molecular biology, vascular tone physiology (exercise)
  • Added value, product reformulation, fortification, supplementation and functional foods
  • Social nutrition
  • Use of validated food diaries and nutrient analysis
  • Access to food and food policy
  • Community and school meals

Membership of professional associations and societies

  • Member of IBMS (2007-date)
  • Member of Phytochemical Society of Europe (2007-date)
  • Member of Nutrition Society (2000-2008)
  • Fellow of the Higher Education Academy

Conference attendance

Sickle Cell and Nutritional Health: Can the type of food we eat help to reduce the sickle cell crisis?A discussion about access to food versus supplementation. International Conference on Health, Wellness and Society. University of California, Berkeley, USA.

Sickle Cell and Nutrition: Can the type of food we eat help to reduce the sickle cell crisis? An invitation to participate in research. Sickle Cell: The Next 100 Years

Sickle Cell and Nutrition: A discission about food versus folic acid supplement. Sickle Cell: The Next 100 Years

Consultancy work


Dr Basten worked on Pepsico's wellness programme by reformulating products to contain less sugar and salt.

One Nottingham / Nottingham City Council / Marmot

Dr Basten investigated how social housing, school meals and nutrition effects social aspiration, health and wellness.

Externally funded research grants information

£40,000 (2008-date)

Dr Basten co-wrote bids for the 3rd sector East Midlands charity as part of the RIF project and received funding from Sport Relief, One Nottingham  and the Big Lottery Fund to allow a community group to develop a healthy cookbook and address health and wellness.

Internally funded research project information

£17000 (2008-date)

  • DMU RIF: Healthy Building Design (PI) 2009-10
  • DMU RIF: Food and Nutrition (PI) 2009-10
  • DMU Teacher Fellow: Technology and Learning (PI) 2010-11
  • DMU Antioxidant Project (I) 2008-2009
  • DMU TQEF: Moodle vs Blackboard (I) 2009
  • DMU RITA: Virtual Analytical Laboratory (I) 2008-9 

Professional esteem indicators

Dr Basten is internationally known for his work on how micronutrients modulate the pathophysiology of disease in the context of early-stage bio-markers in non-invasive surrogare tissue. Immediately prior to DMU, he worked with Prof H J Powers (University of Sheffield) in collaboration with Paul Finglas (Institute of Food Research)on the relationship between folate status and biomarkers of cardiovascular disease, cancer and health. The intervention work looked at food intervention vs supplementation using food diaries, 24 hour recall and clinical markers.

In collaboration with Dr S J Duthie (Rowett Research Institute) he validated biomarkers of DNA instability, showed that folate supplementation elicited a significant reduction in uracil misincorporation in healthy people, and developed an automated method to measure folate in lymphocytes and buccal cells.

With Prof S A Watson (University of Nottingham) he showed that hyperplastic polyps have elevated levels of pre-cancerous biomarkers compared with normal resection colorectal samples. In a European Union project co-ordinated by Prof I T Johnson and Prof G Williamson (Institute of Food Research) he investigated the induction of phase II detoxification enzymes (ie human bilirubin UDP-glucuronosyl transferase) and apoptosis by glucosinolate derived isothiocyantes. Also with Prof A J Knox (Nottingham City Hospital) he elucidated how cGMP modulates nitric oxide levels in asthma and cyctic fibrosis patients.


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